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Aloe Sabila / Aloe vera / ALOE VERA |
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Other scientific
names |
Common names |
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Aloe barbadensis |
Acibar (Span.) |
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Aloe elongata |
Dilang-boaia (Bik.) |
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Aloe humilis |
Dilang buaya (Bik.) |
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Aloe perfoliata |
Dilang-halo (Bis.) |
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Aloe vulgaris |
Penca sabila (Spanish) |
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Sabila (Tag.) |
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Sabila pinya (Tag.) |
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Barbados aloe (Engl.) |
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Aloe vera (English) |
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Botany
Herb 30 to 40 cm high; leaves
arising from the ground, smooth,
thick, fleshy, mucilagenous,
succulent, narrow-lanceolate, 20
to 50 cm long, 5 to 8 cm wide,
tapering, light green with white
blotches, spiny-toothed margins;
flowering stalk erect, usually
twice the height of the plant;
flowers yellow, 2 to 3 cm long.
Properties
• Aromatic, astringent, aperient,
purgative, emmenagogue,
emollient, cholagogue, laxative,
stomachic, tonic, vulnerary.
• Considered antitoxic,
anticancer, antimutagenic.
Constituents
Aloin; barbaloin, 25%;
isobarbaloin resin, 12.5%; (sicaloin;
emodin; cinnamic acid; b-arabinose;
oxidase); cinnamic acid; resin
up to 20% (aloesin, aloesone,
aloeresin A and C); coumarins,
traces of volatile oil.
Distribution and Production
Commonly raised in clay pots or
perforated containers. Sporadic
in the yard; ordinary garden
soil with compost is best.
Regenerates its growth as lower
leaves are cut, perpetuating
availability of the material.
Parts utilized
Leaves, pulp, and sap.
Dried juice from leaves.
Harvest mature leaves and rinse
with water; remove spines prior
to use.
Uses
Folkloric
Dandruff.
Fresh juice expressed from the
leaves is spread on skin burns,
scalds, scrapes, sunburn and
wounds.
Burns and scalds: Use ointment
made by mixing equal amounts of
powdered aloe and coconut oil.
Wound healing.
Conjunctivitis: Apply the juice
to the outer eyelid.
Sprains, sore throat.
In small doses, used as a tonic.
Contusions or local edema:
Bruise fresh leaves and apply as
poultice over affected areas.
Alopecia and falling hair:
Remove spines, cut leaves and
rub directly on the scalp. The
juice of fresh leave may be
mixed with gogo and used as a
shampoo.
Juice mixed with coconut milk
used for dysentery and kidney
pains.
Bruises: Equal parts of juice
and alcohol, then applied to
affected areas.
Hemorrhoids: Cuticle from leaves
used as suppository for
hemorrhoids.
In the Arabian peninsula, used
for diabetes.
New uses
Benefits are derived from a
combination of all active
components; the aequous form
provides the most benefits.
Widely used in cosmetic
preparations.
Salicylic acid content can
inhibit prostaglandin and
thromboxane formation by
blocking the arachidonic acid
cascade.
UV-B protection through cinnamic
acid.
Caution !
Not for internal use.
Some mineral cyto-toxicity of
the juice. Should be rinsed off
after 30 minutes.
Studies
• Laxative: Aloin is the
presumed laxative component of
aloe. Further studies are needed
to establish the dose and safety.
• Genital Herpes: Limited
evidence for extract of aloe
vera in a hydrophilic cream
preparation for use in treatment
for genital herpes.
• Psoriasis vulgaris: Evidence
suggests aloe extract in
hydrophilic creams to be of
benefit in psoriasis vulgaris.
• Dandruff: Studies suggest
effectiveness for treatment of
seborrheic dermatitis.
• Other promising with postiive
results for use in canker sores
(aphthous stomatitis), lichen
planus, ulcertaive colitis,
wound healing, skin burns.
• Antigenotoxic: Study showed
antigenotoxic potentials of aloe
and suggests a potential use in
prevention of DNA damage caused
by chemical agents.
• Psoriasis vulgaris: A double-blind
placebo-controlled study to
evaluate the efficacy and
tolerability of topical Aloe
vera in a hydrophilic creams
showed it to be more effective
than placebo without toxic or
objective side effects and can
be considered a safe alternative
treatment for psoriasis.
• Anti-leukemic / Anti-Mutagenic:
Study isolated di(2-ethylhexyl)phthalate
(DEHP) from Aloe vera. It
exhibited growth inhibition
against three leukemic cell
lines and reduced AF-2-induced
mutagenicity. DEHP was
considered the active principle
responsible for the anti-leukemic
and anti-mutagenic effects in
vitro.
• Acemannan / Macrophage
Activation: Study isolated a
major carbohydrate fraction from
the gell of Aloe vera leaf. It
has been claimed to accelerate
wound healing, immune
stimulation and have anti-cancer
and anti-viral effects. Study
showed acemannan stimulate
cytokine production, nitric
oxide release. The production of
cytokines IL-6 and TNF-alpha
were acemannan dose-dependent.
The results suggest acemannan
may function, in part, through
macrophage activation.
• Aloeride / Immunostimulatory
Activity: Study characterized a
new immunostimulatory
polysaccharide, Aloeride, from
commercial aloe vera juice.
• Aloe-emodin / Anticancer /
Antiproliferative: Study showed
aloe-emodin inhibited cell
proliferation and induced
apoptosis in two human liver
cancer cell lines, but with
different antiproliferative
mechanisms. Results suggest
aloe-emodin may be useful in
liver cancer prevention.
• Biochemotherapy: Study showed
percentage of both objective
tumor regressions and disease
control was significantly higher
in patients concomitantly
treated with Aloe than with
chemotherapy alone. Study
suggest Aloe may be beneficial
to use with chemotherapy to
increase efficacy in terms of
both tumore regression and
survival time.
• Antidiabetic: (1) In a study
of patients with non-insulin
diabetes and Swiss albino mice
with aloxan-induced diabetes,
lowering of blood sugars was
noted by as yet unknown
mechanisms. (2) In a study of 5
plants used by Kuwaiti diabetics,
only extracts with myrrh and
Aloe gums effectively increase
glucose tolearance in both
normal and diabetic rats.
• Burn Wound Healing: Based on
meta-analysis using duration of
wound healing as the outcome
measure, the healing time of the
aloe vera group was 8.79 days
shorted than the control group.
Cumulative evidence supports
aloe vera as beneficial
intervention for burn wound
healing in first to second
degree burns.
Availability
Wild-crafted.
Cultivated for ornamental and
medicinal use.
Ingredients to many commercial
hair/cosmetic products.
Gels and other products in the
cybermarket.
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Tomado de:
http://www.stuartxchange.com/Sabila.html
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Additional Sources and Suggested
Readings
(1)
Aloe (Aloe vera) /
Drugs and Supplements
(2)
ANTI-GENOTOXIC EFFECT OF ALOE
VERA GELR ON THE MUTAGENIC
ACTION OF ETHYL METHANESULFONATE
Arch. Biol. Sci., Belgrade, 59
(3), 223-226, 2007. / DOI:10.2298/ABS0703223S
(3)
Management of psoriasis with
Aloe vera extract in a
hydrophilic cream: a
placebo-controlled, double-blind
study
Tropical Medicine &
International Health, Volume 1,
Number 4, August 1996 , pp.
505-509
(4)
Anti-leukaemic and
anti-mutagenic effects of
di(2-ethylhexyl)phthalate
isolated from Aloe vera Linne
/ Lee K H et al / J Pharm
Pharmacol. 2000 May;52(5):593-8.
(5)
Activation of a mouse macrophage
cell line by acemannan: the
major carbohydrate fraction from
Aloe vera gel / Zhang L and
Tizard IR / Immunopharmacology.
1996 Nov;35(2):119-28.
(6)
Characterization of Aloeride, a
new high-molecular-weight
polysaccharide from Aloe vera
with potent immunostimulatory
activity / Pugh N et al / J
Agric Food Chem. 2001 Feb;49(2):1030-4
(7)
The antiproliferative activity
of aloe-emodin is through
p53-dependent and p21-dependent
apoptotic pathway in human
hepatoma cell lines / Kuo P
L et al / Life Sci. 2002 Sep
6;71(16):1879-92
(8)
A randomized study of
chemotherapy versus
biochemotherapy with
chemotherapy plus Aloe
arborescens in patients with
metastatic cancer / Lissoni
P et al / In Vivo. 2009 Jan-Feb;23(1):171-5
(9)
Studies On The Activity Of
Individual Plants Of An
Antidiabetic Plant Mixture /
Al-Awadi FM and Gumaa KA / Acta
Diabetol Lat Jan-Mar 1987, 24(1)
p37-41
(10)
Antidiabetic Activity Of Aloes:
Preliminary Clinical &
Experimental Observations /
Ghannam N et al / Horm Res
24(4):288-94 1986
(11)
The efficacy of aloe vera used
for burn wound healing: A
systematic review / R.
Maenthaisong et al / Burns,
Volume 33, Issue 6, Pages
713-718 |
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